The 2018 Wyoming Cowboys football team represented the University of Wyoming during the 2018 NCAA Division I FBS football season. The Cowboys are coached by fifth-year head coach Craig Bohl and play their home games at War Memorial Stadium as a member of the Mountain Division of the Mountain West Conference. They finished the regular season 6–6, 4–4 in Mountain West play to finish in third place in the Mountain division. Despite being bowl eligible, they were not invited to a bowl game.