The 2018 SMU Mustangs football team represented Southern Methodist University in the 2018 NCAA Division I FBS football season. The Mustangs played their home games at Gerald J. Ford Stadium in Dallas, Texas and competed in the West Division of the American Athletic Conference. They were led by first-year coach Sonny Dykes. They finished the season 5–7, 4–4 in American Athletic play to finish in fourth place in the West Division.