The 2018 Copa Colombia, officially the 2018 Copa Águila for sponsorship reasons, was the 16th edition of the Copa Colombia, the national cup competition for clubs of DIMAYOR. The tournament was contested by 36 teams. Junior were the defending champions, but were knocked out by Atlético Nacional in the quarterfinals. Atlético Nacional were the champions after beating Once Caldas 4–3 on aggregate in the final, and qualified for the 2019 Copa Libertadores.