The 2018–19 Evansville Purple Aces women's basketball team represents the University of Evansville during the 2018–19 NCAA Division I women's basketball season. The Purple Aces, led by third year head coach Matt Ruffing, play their home games at Meeks Family Fieldhouse and were members of the Missouri Valley Conference. They finished the season 4–26, 2–16 in MVC play to finish in last place. They lost in the first round of the Missouri Valley women's tournament to Loyola–Chicago.