The 2017–18 Southern Illinois women's basketball team represents Southern Illinois University Carbondale during the 2017–18 NCAA Division I women's basketball season. The Salukis were led by fifth year head coach Cindy Stein. They play their home games at SIU Arena and were members of the Missouri Valley Conference. They finished the season 17–14, 11–7 in MVC play to finish in fourth place. They advanced to the semifinals of the Missouri Valley women's tournament where they lost to Drake.