The 2017–18 Ole Miss Rebels men's basketball team represented the University of Mississippi in the 2017–18 NCAA Division I men's basketball season, their 108th basketball season. They were coached by Andy Kennedy for the first 27 games of the season before he left the position on February 19, 2018. The Rebels named assistant coach Tony Madlock interim head coach for the remainder of the season. The Rebels played their second full season in The Pavilion at Ole Miss in Oxford, Mississippi as members of the Southeastern Conference. They finished the season 12–20, 5–13 in SEC play to finish in last place. They lost in the first round of the SEC tournament to South Carolina.