The 2016–17 Clemson Tigers women's basketball team represented Clemson University during the 2016–17 college basketball season. The Tigers were led by fourth-year head coach Audra Smith. The Tigers, members of the Atlantic Coast Conference, played their home games at Littlejohn Coliseum after a one year of renovation. They finished the season 15–16, 3–13 in ACC play to finish in a tie for thirteenth place. They advance to the second round of ACC women's tournament where they lost to Louisville.