The 2015–16 Houston Cougars women's basketball team represented the University of Houston during the 2015–16 NCAA Division I women's basketball season. The season marked the third for the Cougars as members of the American Athletic Conference. The Cougars, led by second year head coach , played their home games at Hofheinz Pavilion. They finished the season 6–24, 2–16 in The American play to finish in last place. They lost in the first round of American Athletic women's tournament to Tulsa.