The 2015–16 Buffalo Bulls women's basketball team represents the University at Buffalo during the 2015–16 NCAA Division I women's basketball season. The Bulls, led by fourth year head coach Felisha Legette-Jack, play their home games at Alumni Arena as members of the East Division of the Mid-American Conference. They finished the season 20–14, 8–10 in MAC play to finish in third place in the East Division. They won the MAC women's tournament and earn an automatic trip to the NCAA women's tournament for the first time in school history where they lost in the first round to Ohio State.