The 2008 Crewe and Nantwich by-election was a parliamentary by-election held on 22 May 2008, for the House of Commons constituency of Crewe and Nantwich, in Cheshire, England. The election was won by the Conservative party candidate Edward Timpson, who defeated the Labour party candidate Tamsin Dunwoody, on a swing from Labour to Conservative of 17.6%, a swing that in a general election would have seen nine Labour cabinet ministers lose their seats.