The 2006 Plymouth City Council election was held on 4 May 2006 to elect members of Plymouth City Council in England. One third of the council was up for election on the day, with an additional seat in Southway Ward remaining vacant until a by-election on 22 June. After the election, Labour were reduced to 28 out of the 56 filled seats, thus temporarily losing control of the council to No Overall Control. However, Labour won the Southway by-election on 22 June, thus restoring their overall control of the council.