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About: 2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Stimulation105827684, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substancePill (pharmacy)yago:WikicatStimulantsyago:Abstraction100002137yago:Cognition100023271yago:Information105816287yago:PsychologicalFeature100023100drugyago:Stimulation105827684 New Facet based on Instances of this Class

2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine is a drug originally researched as a potential opioid analgesic, but was found to be inactive in this assay, and relatively toxic to mice. Subsequently it was found to possess activity as an agonist at nicotinic acetylcholine receptors during the course of work that ultimately led to the discovery of the anti-smoking drug varenicline.