The 1994–95 Saint Louis Billikens men's basketball team represented Saint Louis University in the 1994–95 NCAA Division I men's basketball season. The Billikens were led by head coach Charlie Spoonhour who was in his third season at Saint Louis. The team played their home games at the brand new Kiel Center and were a member of the Great Midwest Conference. The Billikens finished the season 23–8, 8–4 in GMC play to finish 2nd. They lost in the championship game of the GMC tournament, but received an at-large bid to the NCAA tournament as No. 9 seed in the East region. The Billikens eliminated Minnesota in the opening round before they were defeated by No. 1 seed and Wake Forest in the second round.