The 1963 Wyoming Cowboys football team represented the University of Wyoming in the Western Athletic Conference (WAC) during the 1963 NCAA University Division football season. In their second season under head coach Lloyd Eaton, the Cowboys compiled a 6–4 record (2–3 against conference opponents), finished fifth in the WAC, and outscored opponents by a total of 191 to 152. Mack Balls and Tom Delaney were the team captains.