The 1922 Oklahoma A&M Aggies football team represented Oklahoma A&M College as a member of the Oklahoma Intercollegiate Conference (OIC) and the Southwest Conference (SWC) during the 1922 college football season. This was the 22nd year of football at A&M and the second under John Maulbetsch. The Aggies played their home games at Lewis Field in Stillwater, Oklahoma. They finished the season 4–4–1 overall, 2–0 in OIC play, and 2–3 in the SWC play.