The 10th United States Colored Heavy Artillery Regiment was an artillery regiment in the Union Army during the American Civil War that served in the New Orleans defenses. The unit was organized in New Orleans in November 1862 as the 1st Louisiana Heavy Artillery Regiment (African Descent), and redesignated as the 1st Corps d'Afrique Heavy Artillery Regiment a year later. It briefly became the 7th United States Colored Heavy Artillery Regiment in April 1864, then assumed its final designation in May.