The .450 Rigby is a rifle cartridge designed in 1994 by John Rigby & Co. for the hunting of large, thick-skinned dangerous game animals in Africa. The cartridge is based on the .416 Rigby necked up to accept a .458 in (11.6 mm) bullet and is intended for use in magazine rifles. The cartridge should not be confused with .450 Nitro Express which was introduced by Rigby in 1898, and is a rimmed cartridge intended for use in double rifles.