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About: Hepatic veno-occlusive disease     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:AilmentCondition, within Data Space : dbpedia.org associated with source document(s)

Type: ThingDiseaseyago:WikicatBiliaryTractDisordersyago:WikicatBloodDisordersyago:Abstraction100002137yago:Attribute100024264yago:BloodDisease114189204yago:BloodDyscrasia114053850yago:Condition113920835yago:Disease114070360yago:Disorder114052403yago:Dyscrasia114053717yago:IllHealth114052046yago:Illness114061805yago:PathologicalState114051917yago:PhysicalCondition114034177diseaseyago:State100024720umbel-rc:AilmentCondition New Facet based on Instances of this Class

Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant and/or excessive exposure to hepatotoxic pyrrolizidine alkaloids. It is classically marked by weight gain due to fluid retention, increased liver size, and raised levels of bilirubin in the blood. The name sinusoidal obstruction syndrome (SOS) is preferred if hepatic veno-occlusive disease happens as a result of chemotherapy or bone marrow transplantation.