William Chamberlaine (March 1, 1871 – June 8, 1925) was a career officer in the United States Army. A graduate of the United States Military Academy and a veteran of the Spanish–American War, Chamberlaine was most notable for his service as a brigadier general in charge of artillery units during World War I. Chamberlaine served as commander of two artillery brigades during World War I, including the Battle of Belleau Wood. He subsequently commanded the American Expeditionary Force's Railway Artillery Reserve, including combat during the Battle of Saint-Mihiel and the Meuse-Argonne Offensive.