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About: WIN 55,212-2     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Whole105869584, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatWINCompoundsyago:Abstraction100002137yago:Cognition100023271yago:Compound105870180yago:Concept105835747yago:Content105809192yago:Idea105833840yago:PsychologicalFeature100023100chemical compounddrugyago:Whole105869584 New Facet based on Instances of this Class

WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical structure. WIN 55,212-2 is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling. At 5 μM WIN 55,212-2 inhibits ATP production in sperm in a CB1 receptor-dependent fashion.