Vincenzina Cusmano (6 January 1826 - 2 February 1894) was an Italian Roman Catholic professed religious from the Sisters Servants of the Poor. Her brother was Giacomo Cusmano; she joined his religious congregation as the two tended to the poor in Palermo. Her original intention was to become a cloistered Carmelite nun though was forced to abandon this desire after her mother died; her mother's death during an epidemic meant that she had to assume care for her siblings since she was the eldest one. Cusmano tended to the poor in Palermo and often worked alongside her brother in this venture until his death in 1888; she continued his work as the Superior General for her order until her own death.