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About: Valspodar     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatExperimentalCancerDrugs, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:Agent114778436yago:Antineoplastic102722458yago:CausalAgent100007347yago:CytotoxicDrug103157987yago:Drug103247620yago:Matter100020827yago:Medicine103740161yago:PhysicalEntity100001930chemical compounddrugyago:Substance100020090yago:WikicatExperimentalCancerDrugs New Facet based on Instances of this Class

Valspodar (PSC833) is an experimental cancer treatment and chemosensitizer. It is a derivative of ciclosporin D (cyclosporin D). Its primary use is as an inhibitor of the efflux transporter P-glycoprotein. Previous studies in animal models have found it to be effective at preventing cancer cell resistance to chemotherapeutics, but these findings did not translate to clinical success.