U.S. Route 280 (US 280) is a spur of U.S. Highway 80. It currently runs for 392 miles (631 km) from Blichton, Georgia at US 80 to Birmingham, Alabama at I-20/I-59. For much of its route, US 280 travels through rural areas and smaller cities in southern Georgia and east central Alabama. Once the highway approaches Birmingham, it is a major suburban route. Numerous shopping centers are located on US 280 throughout northern Shelby County and southern Jefferson County. US 280 is the main connector between Birmingham, AL and Auburn, AL.