Tolly Salvatory Augustine Mbwette (8 June 1956 – 2 July 2020) was a Tanzanian academic, engineer and educator. He held various positions in national and international institutions of higher learning over his lifetime, including that of vice chancellor of the Open University of Tanzania. He was a team leader for various multi-disciplinary research teams responsible for both drinking and wastewater treatment systems that rely on bio-systems. Mbwette also participated in a number of co-operation programmes between European and American institutions and African universities.