Sir John Bowyer, 1st Baronet (21 September 1623 – 18 July 1666) was a 17th-century English soldier and politician. Bowyer was the son of Sir William Bowyer, a wealthy Staffordshire landowner of Knypersley Hall, near Biddulph and his wife Hester Skeffington. On the Restoration, as Colonel of the Staffordshire Militia, he arrested Maj-Gen Thomas Harrison as one of the Regicides of Charles I. Bowyer was created a baronet by Charles II on 11 September 1660. He was High Sheriff of Staffordshire in 1662.