The mixed (or "open") ISSF 25 meter rapid fire pistol was a shooting sports event held as part of the Shooting at the 1968 Summer Olympics programme. It was the 13th appearance of the event. The competition was held on 22 to 23 October 1968 at the Vicente Suárez Shooting Range in Mexico City. 56 shooters from 34 nations competed. Nations had been limited to two shooters each since the 1952 Games. The event was won by Józef Zapędzki of Poland, the nation's first medal in the event and the first of two victories of Zapędzki (who would repeat in 1972). Marcel Roșca's silver put Romania on the rapid fire pistol podium for the fourth time in five Games. Renart Suleymanov of the Soviet Union took bronze.