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Ricasetron (BRL-46470) is a drug which acts as a selective antagonist at the serotonin 5-HT3 receptor. It has antiemetic effects as with other 5-HT3 antagonists, and also has anxiolytic effects significantly stronger than other related drugs, and with less side effects than benzodiazepine anxiolytics. However, it has never been developed for medical use.

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rdfs:label
  • リカセトロン (ja)
  • Ricasetron (en)
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  • Ricasetron (BRL-46470) is a drug which acts as a selective antagonist at the serotonin 5-HT3 receptor. It has antiemetic effects as with other 5-HT3 antagonists, and also has anxiolytic effects significantly stronger than other related drugs, and with less side effects than benzodiazepine anxiolytics. However, it has never been developed for medical use. (en)
  • リカセトロン(Ricasetron, BRL-446470)は、セロトニンのの選択的アンタゴニストとして作用する薬剤である。他のと同様に、制吐薬としての作用を持つ。また、関連の薬剤よりもかなり強い抗不安薬の作用も持ち、ベンゾジアゼピン系の抗不安薬と比べて副作用は少ない。しかし、医療用途の開発はなされなかった。 (ja)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Ricasetron.svg
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ATC prefix
  • none (en)
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IUPAC name
  • endo-N--2,3-dihydro-3,3-dimethyl-indole-1-carboxamide (en)
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PubChem
SMILES
  • CC1C (en)
StdInChI
StdInChIKey
  • ILXWRFDRNAKTDD-QDMKHBRRSA-N (en)
UNII
  • R92JB88O88 (en)
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  • changed (en)
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  • changed (en)
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  • Ricasetron (BRL-46470) is a drug which acts as a selective antagonist at the serotonin 5-HT3 receptor. It has antiemetic effects as with other 5-HT3 antagonists, and also has anxiolytic effects significantly stronger than other related drugs, and with less side effects than benzodiazepine anxiolytics. However, it has never been developed for medical use. (en)
  • リカセトロン(Ricasetron, BRL-446470)は、セロトニンのの選択的アンタゴニストとして作用する薬剤である。他のと同様に、制吐薬としての作用を持つ。また、関連の薬剤よりもかなり強い抗不安薬の作用も持ち、ベンゾジアゼピン系の抗不安薬と比べて副作用は少ない。しかし、医療用途の開発はなされなかった。 (ja)
IUPHAR ligand
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CAS number
  • 117086-68-7
ChEMBL
  • 2105377
FDA UNII code
  • R92JB88O88
PubChem
  • 14850173
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