A rheumatoid nodule is a lump of tissue, or an area of swelling, that appear on the exterior of the skin usually around the olecranon (tip of the elbow) or the interphalangeal joints (finger knuckles), but can appear in other areas. There are four different types of rheumatoid nodules: subcutaneous rheumatoid nodules, cardiac nodules, pulmonary nodules, and central nervous systems nodules. These nodules occur almost exclusively in association with rheumatoid arthritis. Very rarely do rheumatoid nodules occur as rheumatoid nodulosis (multiple nodules on the hands or other areas) in the absence of rheumatoid arthritis. Rheumatoid nodules can also appear in other areas of the body other than the skin. Less commonly they occur in the lining of the lung or other internal organs. The occurrence
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| - Rheumaknoten (de)
- Nodule rhumatoïde (fr)
- Rheumatoid nodule (en)
- Guzek reumatoidalny (pl)
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| - Bei Rheumaknoten handelt es sich um Knoten, die unter der Haut liegen und die als klinisches Symptom typisch für die rheumatoide Arthritis (Synonym: chronische Polyarthritis) sind. (de)
- Les nodules rhumatoïdes sont des irrégularités des tissus observées sous la peau, sous la plèvre ou dans la membrane synoviale dans la polyarthrite rhumatoïde. Dans la peau, les nodules rhumatoïdes sont des nodosités sous-cutanées fermes mobiles et indolores, présentes principalement sur les et les faces dorsales des doigts. (fr)
- Guzki reumatoidalne – niebolesne zmiany występujące u około 20% chorych na reumatoidalne zapalenie stawów. Zbudowane są z włóknikowego ośrodka, dookoła którego gromadzą się fibroblasty i inne komórki, ułożone palisadowato. Zlokalizowane są podskórnie lub w ścięgnach, zwykle nad wyprostnymi powierzchniami stawów. (pl)
- A rheumatoid nodule is a lump of tissue, or an area of swelling, that appear on the exterior of the skin usually around the olecranon (tip of the elbow) or the interphalangeal joints (finger knuckles), but can appear in other areas. There are four different types of rheumatoid nodules: subcutaneous rheumatoid nodules, cardiac nodules, pulmonary nodules, and central nervous systems nodules. These nodules occur almost exclusively in association with rheumatoid arthritis. Very rarely do rheumatoid nodules occur as rheumatoid nodulosis (multiple nodules on the hands or other areas) in the absence of rheumatoid arthritis. Rheumatoid nodules can also appear in other areas of the body other than the skin. Less commonly they occur in the lining of the lung or other internal organs. The occurrence (en)
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| - Micrograph of a rheumatoid nodule, showing the characteristic palisading granuloma with a core consisting of necrotic collagen and fibrin. H&E stain. (en)
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| - Bei Rheumaknoten handelt es sich um Knoten, die unter der Haut liegen und die als klinisches Symptom typisch für die rheumatoide Arthritis (Synonym: chronische Polyarthritis) sind. (de)
- Les nodules rhumatoïdes sont des irrégularités des tissus observées sous la peau, sous la plèvre ou dans la membrane synoviale dans la polyarthrite rhumatoïde. Dans la peau, les nodules rhumatoïdes sont des nodosités sous-cutanées fermes mobiles et indolores, présentes principalement sur les et les faces dorsales des doigts. (fr)
- A rheumatoid nodule is a lump of tissue, or an area of swelling, that appear on the exterior of the skin usually around the olecranon (tip of the elbow) or the interphalangeal joints (finger knuckles), but can appear in other areas. There are four different types of rheumatoid nodules: subcutaneous rheumatoid nodules, cardiac nodules, pulmonary nodules, and central nervous systems nodules. These nodules occur almost exclusively in association with rheumatoid arthritis. Very rarely do rheumatoid nodules occur as rheumatoid nodulosis (multiple nodules on the hands or other areas) in the absence of rheumatoid arthritis. Rheumatoid nodules can also appear in other areas of the body other than the skin. Less commonly they occur in the lining of the lung or other internal organs. The occurrence of nodules in the lung of miners exposed to silica dust was known as Caplan’s syndrome. Rarely, the nodules occur at diverse sites on body (e.g. upper eyelid, distal region of the soles of the feet, vulva and internally in the gallbladder, lung, heart valves, larynx, and spine). Rheumatoid nodules can vary in size from 2 mm to 5 cm and are usually rather firm to the touch. Quite often they are associated with synovial pockets or bursae. About 5% of people with rheumatoid arthritis have such nodules within two years of disease onset, and the cumulative prevalence is about 20 to 30%. Risk factors of developing rheumatoid nodules include as smoking and trauma to small vessels. In the majority of the time, nodules are not painful or disabling in any way. They are usually more of an unsightly nuisance. However, rheumatoid nodules can become painful when infection or ulcers occur on the skin of the nodule. Some nodules can actually disappear over time, but other times, they can grow larger making prediction of nodular size difficult to predict. Treatment also can be quite difficult, but surgical removal and injection of corticosteroids have both shown good results towards the treatment for rheumatoid nodules. (en)
- Guzki reumatoidalne – niebolesne zmiany występujące u około 20% chorych na reumatoidalne zapalenie stawów. Zbudowane są z włóknikowego ośrodka, dookoła którego gromadzą się fibroblasty i inne komórki, ułożone palisadowato. Zlokalizowane są podskórnie lub w ścięgnach, zwykle nad wyprostnymi powierzchniami stawów. (pl)
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