About: Retroviral matrix protein

Facets (new session)
Description
Metadata
Settings
- Rule:
- Inverse Functional Properties:
- "Same As":

About: Retroviral matrix protein Goto Sponge NotDistinct Permalink

An Entity of Type : yago:WikicatProteinFamilies, within Data Space : dbpedia.org associated with source document(s)
QRcode icon

http://dbpedia.org/describe/?url=http%3A%2F%2Fdbpedia.org%2Fresource%2FRetroviral_matrix_protein&graph=http%3A%2F%2Fdbpedia.org&graph=http%3A%2F%2Fdbpedia.org

Retroviral matrix proteins are components of envelope-associated capsids of retroviruses. These proteins line the inner surface of viral envelopes and are associated with viral membranes. Matrix proteins are produced as N-terminal domains of Gag precursor polyproteins. The Gag polyprotein directs the assembly and release of virus particles from infected cells. The Gag polyprotein has three domains required for activity: an N-terminal membrane-binding (M) domain (which corresponds to the matrix protein) that directs Gag to the plasma membrane, an interaction (I) domain involved in Gag aggregation, and a late assembly (L) domain that mediates the budding process . During viral maturation, the Gag polyprotein is cleaved by the retroviral protease into several corresponding structural proteins

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Protein yago:Abstraction100002137 yago:Family108078020 yago:Group100031264 yago:Organization108008335 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity organisation protein yago:SocialGroup107950920 yago:Unit108189659 yago:WikicatProteinFamilies
rdfs:label	Retroviral matrix protein (en)
rdfs:comment	Retroviral matrix proteins are components of envelope-associated capsids of retroviruses. These proteins line the inner surface of viral envelopes and are associated with viral membranes. Matrix proteins are produced as N-terminal domains of Gag precursor polyproteins. The Gag polyprotein directs the assembly and release of virus particles from infected cells. The Gag polyprotein has three domains required for activity: an N-terminal membrane-binding (M) domain (which corresponds to the matrix protein) that directs Gag to the plasma membrane, an interaction (I) domain involved in Gag aggregation, and a late assembly (L) domain that mediates the budding process . During viral maturation, the Gag polyprotein is cleaved by the retroviral protease into several corresponding structural proteins (en)
name	Gag_MA (en) Gag_p10 (en) Gag_p15 (en) Retro_M (en)
foaf:depiction
dcterms:subject	Retroviridae Protein families Viral protein class
Wikipage page ID	32073606 (xsd:integer)
Wikipage revision ID	1122309134 (xsd:integer)
Link from a Wikipage to another Wikipage	Endogenous retrovirus Plasma membrane Peptide Retroviruses Retroviridae Protein families Mason-Pfizer monkey virus Genome Viral protein class Feline leukemia virus Gammaretrovirus Alpha helix Eukaryotic Capsid Protein domain Viral envelope Protein Feline sarcoma virus Primary sequence Murine leukemia virus Protein precursor Mouse mammary tumor virus P24 capsid protein Viral budding Gag polyprotein Secondary structure Retroviral protease Nucleocapsid Beta-retrovirus
sameAs	Retroviral matrix protein Retroviral matrix protein Retroviral matrix protein Retroviral matrix protein
dbp:wikiPageUsesTemplate	dbt:Infobox_protein_family dbt:InterPro_content dbt:Reflist dbt:Viral_proteins
thumbnail	wiki-commons:Special:FilePath/PDB_1mn8_EBI.jpg?width=300
SCOP	1 (xsd:integer) 6.0 (second)
caption	solution structure of the m-pmv wild type matrix protein (en) structure of moloney murine leukaemia virus matrix protein (en) m-domain from gag polyprotein of rous sarcoma virus, nmr, 20 structures (en) crystal structure of equine infectious anaemia virus matrix antigen (en)
InterPro	IPR000840 (en) IPR003322 (en) IPR004028 (en) IPR014834 (en)
Pfam	PF01140 (en) PF02337 (en) PF02813 (en) PF08723 (en)
Pfam clan	CL0074 (en)
symbol	Gag_MA (en) Gag_p10 (en) Gag_p15 (en) Retro_M (en)
has abstract	Retroviral matrix proteins are components of envelope-associated capsids of retroviruses. These proteins line the inner surface of viral envelopes and are associated with viral membranes. Matrix proteins are produced as N-terminal domains of Gag precursor polyproteins. The Gag polyprotein directs the assembly and release of virus particles from infected cells. The Gag polyprotein has three domains required for activity: an N-terminal membrane-binding (M) domain (which corresponds to the matrix protein) that directs Gag to the plasma membrane, an interaction (I) domain involved in Gag aggregation, and a late assembly (L) domain that mediates the budding process . During viral maturation, the Gag polyprotein is cleaved by the retroviral protease into several corresponding structural proteins, yielding the matrix (MA), capsid (CA), and nucleocapsid (NC) proteins, and some smaller peptides. Gag-derived proteins govern the entire assembly and release of the virus particles, with matrix proteins playing key roles in Gag stability, capsid assembly, transport and budding. (en)
OPM family	42 (xsd:integer) 44 (xsd:integer)
OPM protein	1 (xsd:integer) 2 (xsd:integer) 6.0 (second)
gold:hypernym	Components
prov:wasDerivedFrom	wikipedia-en:Retroviral_matrix_protein?oldid=1122309134&ns=0
page length (characters) of wiki page	7089 (xsd:nonNegativeInteger)
Symbol	Gag_MA Gag_p10 Gag_p15

Faceted Search & Find service v1.17_git139 as of Feb 29 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 08.03.3330 as of Mar 19 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (62 GB total memory, 43 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software