About: Protein–protein interaction prediction

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Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes.

Attributes	Values
rdfs:label	تنبؤ بتآثر بروتين-بروتين (ar) Protein–protein interaction prediction (en)
rdfs:comment	التنبؤ بتآثر بروتين-بروتين (بالإنجليزية: Protein–protein interaction prediction)‏ هو مجال يجمع بين المعلوماتية الحيوية وعلم الأحياء البنيوي في محاولةٍ لتحديد وفهرسة التآثرات الفيزيائية بين أزواج أو مجموعات البروتينات. فهم تآثرات البروتين-بروتين مهم في سبيل تقصي مسارات التأشير داخل الخلوية، نمذجة وتحديد بنُى المركبات البروتينية وللحصول على رؤىً وأفكارٍ حول مختلف العمليات البيوكيميائية. (ar) Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes. (en)
foaf:depiction
dcterms:subject	Proteomics
Wikipage page ID	4350008 (xsd:integer)
Wikipage revision ID	1094199628 (xsd:integer)
Link from a Wikipage to another Wikipage	BLAST Van der Waals radius Interactome Interolog Mass spectrometry Protein function prediction Protein structure prediction Protein–DNA interaction site predictor Protein–protein interaction Gene prediction Clustal Structural biology Protein-fragment complementation assay Protein Data Bank Macromolecular docking Protein microarray Proteomics Tryptophan synthase Escherichia coli FastContact Acetate CoA-transferase Bioinformatics Homology (biology) Src family kinase Phylogenetic profiling Two-hybrid screening Microscale Thermophoresis SH2 domain SH3 domain Protein structure prediction software Protein-protein docking Bayesian method
Link from a Wikipage to an external page	https://img.jgi.doe.gov http://openwetware.org/wiki/Protein-protein_interaction_databases
sameAs	Protein–protein interaction prediction Protein–protein interaction prediction Protein–protein interaction prediction Protein–protein interaction prediction Protein–protein interaction prediction
dbp:wikiPageUsesTemplate	dbt:Protein_methods dbt:R dbt:Reflist dbt:Short_description dbt:Prone_to_spam
thumbnail	wiki-commons:Special:FilePath/Phylogenetic_Profiling_Method.png?width=300
has abstract	التنبؤ بتآثر بروتين-بروتين (بالإنجليزية: Protein–protein interaction prediction)‏ هو مجال يجمع بين المعلوماتية الحيوية وعلم الأحياء البنيوي في محاولةٍ لتحديد وفهرسة التآثرات الفيزيائية بين أزواج أو مجموعات البروتينات. فهم تآثرات البروتين-بروتين مهم في سبيل تقصي مسارات التأشير داخل الخلوية، نمذجة وتحديد بنُى المركبات البروتينية وللحصول على رؤىً وأفكارٍ حول مختلف العمليات البيوكيميائية. تجريبيا، يمكن استنتاج التآثرات الفيزيائية بين أزواج البروتينات من خلال العديد من التقنيات منها: أنظمة الهجينين الخميري، (PCA)، التنقية حسب الألفة/ مطيافية الكتلة، مصفوفات البروتين الدقيقة، (FRET) (MST). هنالك مجهودات جارية لتحديد التآثروم الخاص بالعديد من الأجناس. عادة ما توفر التآثرات المحدَّدَة تجريبيا الأساس للتقنيات الحاسوبية للتنبؤ بالتآثرات المماثلة والشبيهة، على سبيل المثال: استخدام تسلسل بروتيني متماثل بين عدة أجناس. مع ذلك توجد طرق تتنبؤ بتآثرات جديدة من دون وجود معلومات سابقة حول تآثرات مماثلة. (ar) Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes. Experimentally, physical interactions between pairs of proteins can be inferred from a variety of techniques, including yeast two-hybrid systems, protein-fragment complementation assays (PCA), affinity purification/mass spectrometry, protein microarrays, fluorescence resonance energy transfer (FRET), and Microscale Thermophoresis (MST). Efforts to experimentally determine the interactome of numerous species are ongoing. Experimentally determined interactions usually provide the basis for computational methods to predict interactions, e.g. using homologous protein sequences across species. However, there are also methods that predict interactions de novo, without prior knowledge of existing interactions. (en)
gold:hypernym	Field
prov:wasDerivedFrom	wikipedia-en:Protein–protein_interaction_prediction?oldid=1094199628&ns=0
page length (characters) of wiki page	25003 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Protein–protein_interaction_prediction
is Link from a Wikipage to another Wikipage of	Protein function prediction Protein structure prediction Protein–DNA interaction site predictor Protein–protein interaction Gene prediction Protein-protein interaction prediction Protein protein interaction prediction Cytoscape EsyN Homology modeling Human interactome Roger Craig (Jeopardy! contestant) Ruth Nussinov Molecular biology
is Wikipage redirect of	Protein-protein interaction prediction Protein protein interaction prediction
is known for of	Ruth Nussinov
is known for of	Ruth Nussinov
is foaf:primaryTopic of	wikipedia-en:Protein–protein_interaction_prediction

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