The Prospect Park Second Plat Historic District is a nationally recognized historic district located in the north-central section of Des Moines, Iowa, United States. The residential area contained middle to upper class housing that was developed in the late 19th and early 20th centuries in the suburb of North Des Moines. It has been listed on the National Register of Historic Places since 1998. It is part of the Towards a Greater Des Moines MPS.