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Progastrin is an 80-amino acid intracellular protein and the precursor of gastrin, a gastrointestinal hormone produced by G cells in the gastric antrum. The main function of gastrin is to regulate acid secretion. During digestion, only gastrin is released into the bloodstream and stimulates the secretion of hydrochloric acid in the stomach as well as pancreatic digestive enzymes. In humans, progastrin is encoded by the GAST gene. Progastrin is expressed primarily in stomach tissue.

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  • Progastrine (fr)
  • Progastrin (en)
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  • La progastrine est une protéine intracellulaire de 80 acides aminés et le précurseur de la gastrine, une hormone gastrointestinale produite par les cellules G de l'antre gastrique. La fonction principale de la gastrine est de réguler la sécrétion acide. Au cours de la digestion, seule la gastrine est libérée dans le sang et stimule la sécrétion d’acide chlorhydrique dans l’estomac ainsi que celle d’enzymes digestives pancréatiques. Chez l’humain, la progastrine est codée par le gène GAST. La progastrine est principalement exprimée dans les tissus de l’estomac. (fr)
  • Progastrin is an 80-amino acid intracellular protein and the precursor of gastrin, a gastrointestinal hormone produced by G cells in the gastric antrum. The main function of gastrin is to regulate acid secretion. During digestion, only gastrin is released into the bloodstream and stimulates the secretion of hydrochloric acid in the stomach as well as pancreatic digestive enzymes. In humans, progastrin is encoded by the GAST gene. Progastrin is expressed primarily in stomach tissue. (en)
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  • La progastrine est une protéine intracellulaire de 80 acides aminés et le précurseur de la gastrine, une hormone gastrointestinale produite par les cellules G de l'antre gastrique. La fonction principale de la gastrine est de réguler la sécrétion acide. Au cours de la digestion, seule la gastrine est libérée dans le sang et stimule la sécrétion d’acide chlorhydrique dans l’estomac ainsi que celle d’enzymes digestives pancréatiques. Chez l’humain, la progastrine est codée par le gène GAST. La progastrine est principalement exprimée dans les tissus de l’estomac. (fr)
  • Progastrin is an 80-amino acid intracellular protein and the precursor of gastrin, a gastrointestinal hormone produced by G cells in the gastric antrum. The main function of gastrin is to regulate acid secretion. During digestion, only gastrin is released into the bloodstream and stimulates the secretion of hydrochloric acid in the stomach as well as pancreatic digestive enzymes. In humans, progastrin is encoded by the GAST gene. Progastrin is expressed primarily in stomach tissue. (en)
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