About: Pestivirus internal ribosome entry site (IRES)     Goto   Sponge   NotDistinct   Permalink

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This family represents the internal ribosome entry site (IRES) of the pestiviruses. The pestivirus IRES allows cap and end-independent translation of mRNA in the host cell. The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for the eukaryotic initiation factor, eIF4F. The classical swine fever virus UTR described appears to be longer at the 5' end than other pestivirus UTRs. This family represents the conserved core.

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rdf:type
rdfs:label
  • Pestivirus internal ribosome entry site (IRES) (en)
rdfs:comment
  • This family represents the internal ribosome entry site (IRES) of the pestiviruses. The pestivirus IRES allows cap and end-independent translation of mRNA in the host cell. The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for the eukaryotic initiation factor, eIF4F. The classical swine fever virus UTR described appears to be longer at the 5' end than other pestivirus UTRs. This family represents the conserved core. (en)
name
  • Pestivirus internal ribosome entry site (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/RF00209.jpg
dcterms:subject
Wikipage page ID
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sameAs
Tax domain
  • Viruses (en)
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thumbnail
AltSymbols
  • Pesti_IRES (en)
caption
  • Predicted secondary structure and sequence conservation of IRES_Pesti (en)
id
  • RF00209 (en)
symbol
  • IRES_Pesti (en)
has abstract
  • This family represents the internal ribosome entry site (IRES) of the pestiviruses. The pestivirus IRES allows cap and end-independent translation of mRNA in the host cell. The IRES achieves this by mediating the internal initiation of translation by recruiting a ribosomal 43S pre-initiation complex directly to the initiation codon and eliminates the requirement for the eukaryotic initiation factor, eIF4F. The classical swine fever virus UTR described appears to be longer at the 5' end than other pestivirus UTRs. This family represents the conserved core. (en)
Rfam
  • RF00209 (en)
RNA type
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