Pamela Marie Hupp (née Neumann; born October 10, 1958) is an American murderer serving a life sentence in Missouri's Chillicothe Correctional Center for the 2016 shooting of Louis Gumpenberger in her home in O'Fallon, Missouri. Hupp's claim that she had shot Gumpenberger (who had mental and physical disabilities) in self-defense after he pursued her into her home wielding a knife was not accepted by law enforcement. She ultimately entered an Alford plea before charges of first-degree murder and armed criminal action could go to trial.