About: PA clan of proteases     Goto   Sponge   NotDistinct   Permalink

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The PA clan (Proteases of mixed nucleophile, superfamily A) is the largest group of proteases with common ancestry as identified by structural homology. Members have a chymotrypsin-like fold and similar proteolysis mechanisms but can have identity of <10%. The clan contains both cysteine and serine proteases (different nucleophiles). PA clan proteases can be found in plants, animals, fungi, eubacteria, archaea and viruses.

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  • PA clan of proteases (en)
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  • The PA clan (Proteases of mixed nucleophile, superfamily A) is the largest group of proteases with common ancestry as identified by structural homology. Members have a chymotrypsin-like fold and similar proteolysis mechanisms but can have identity of <10%. The clan contains both cysteine and serine proteases (different nucleophiles). PA clan proteases can be found in plants, animals, fungi, eubacteria, archaea and viruses. (en)
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  • PA clan of proteases (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/PA_clan_vs_C04_family_sequence_conservation.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/TEV_protease_beta-barrels.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/PA_clan_structures_10.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Triad_Divergence.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Viral_protease_loop.png
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