Nicole Frank (born 8 September 2003) is an Uruguayan swimmer. In 2019, she represented Uruguay at the World Aquatics Championships held in Gwangju, South Korea. She competed in the women's 200 metre freestyle event and she did not advance to compete in the semi-finals. She also competed in the women's 200 metre individual medley event. She also competed at the 2022 World Aquatics Championships held in Budapest, Hungary. She competed in the women's 100 metre breaststroke and women's 200 metre individual medley events.