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NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

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  • Proteasa NS2-3 (VHC) (es)
  • Protéase NS2/3 (fr)
  • NS2-3 protease (en)
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  • La proteasa NS2-3 es una enzima responsable del procesado proteolítico entre NS2 y NS3, las cuales son proteínas no estructurales que forma parte del ciclo viral del virus de la hepatitis C. La proteasa NS3 del virus de la hepatitis C, por otro lado, es responsable del procesado postraduccional de proteínas no estructurales. Ambas proteasas están directamente implicadas en la replicación del genoma viral. . (es)
  • NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus. (en)
  • La protéase NS2/3 est une protéine non structurelle du virus de l'hépatite C. Il s'agit d'une protéase constituée d'un polypeptide dont la fonction est une autocatalyse en peptides NS2 et NS3. Elle fonctionnerait comme une cystéine protéase ou une métalloprotéase. Son rôle dans le cycle de réplication du virus n'est pas totalement compris. (fr)
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  • La proteasa NS2-3 es una enzima responsable del procesado proteolítico entre NS2 y NS3, las cuales son proteínas no estructurales que forma parte del ciclo viral del virus de la hepatitis C. La proteasa NS3 del virus de la hepatitis C, por otro lado, es responsable del procesado postraduccional de proteínas no estructurales. Ambas proteasas están directamente implicadas en la replicación del genoma viral. . (es)
  • NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus. (en)
  • La protéase NS2/3 est une protéine non structurelle du virus de l'hépatite C. Il s'agit d'une protéase constituée d'un polypeptide dont la fonction est une autocatalyse en peptides NS2 et NS3. Elle fonctionnerait comme une cystéine protéase ou une métalloprotéase. Son rôle dans le cycle de réplication du virus n'est pas totalement compris. (fr)
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