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About: Mecillinam     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatAntibioticsyago:WikicatBeta-lactamAntibioticsyago:WikicatMolecularFormulasyago:Abstraction100002137yago:Agent114778436yago:Antibacterial102716205yago:Antibiotic102716866yago:CausalAgent100007347yago:Communication100033020yago:Drug103247620yago:Formula106816935yago:Matter100020827yago:Medicine103740161yago:Message106598915yago:MolecularFormula106817173yago:PhysicalEntity100001930drugyago:Statement106722453yago:Substance100020090yago:WikicatEnantiopureDrugsumbel-rc:DrugProduct New Facet based on Instances of this Class

Mecillinam (INN) or amdinocillin (USAN) is an extended-spectrum penicillin antibiotic of the amidinopenicillin class that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. It is used primarily in the treatment of urinary tract infections, and has also been used to treat typhoid and paratyphoid fever. Because mecillinam has very low oral bioavailability, an orally active prodrug was developed: pivmecillinam.