Massachusetts House of Representatives' 5th Hampden district in the United States is one of 160 legislative districts included in the lower house of the Massachusetts General Court. It covers the city of Holyoke in Hampden County. Democrat Aaron Vega of Holyoke has represented the district since 2013. Candidates for this district seat in the 2020 Massachusetts general election include Patrick Beaudry and Patricia Duffy. The current district geographic boundary overlaps with that of the Massachusetts Senate's 2nd Hampden and Hampshire district.