Marie-Hélène Mathey Boo Lowumba (born November 30, 1943) was named ambassador of the Democratic Republic of Congo to the United States on January 11, 2022, by Congolese President Félix Tshisekedi. She is preceded by Ambassador François Nkuna Balumuene. Prior to her appointment, she served as Ambassador of the Republic of Congo to Gabon, Minister of Industry, Commerce, and Weights & Measures in the Democratic Republic of Congo, and Director of External Relations and Governance of the World Health Organization (WHO) among other positions. As a descendant of Koko Mwato I, Marie-Hélène Mathey Boo is the 12th Chief of Bokoli (Ngemoboku Clan) in the Democratic Republic of Congo's Mai-Ndombe Province.