Makhdum Sharifi Shirazi (Persian: مخدوم شریفی شیرازی) was a Persian Sunni statesman and author, who served as the minister of religious affairs (sadr) during the reign of Ismail II (r. 1576–77), and ultimately took refuge in the Ottoman Empire, where he wrote the al-Nawaqez le-bonyān al-rawafez, a sizable anti-Shia argumentative book.