Lu Gwei-djen (Chinese: 魯桂珍; pinyin: Lǔ Guìzhēn; Wade–Giles: Lu Kui-chen; July 22, 1904 – November 28, 1991) was a Chinese biochemist and historian. She was an expert on the history of science and technology in China and a researcher of nutriology. She was an important researcher and co-author of the project Science and Civilisation in China led by Joseph Needham.