Louisiana Highway 54 (LA 54) is a state highway located in St. John the Baptist Parish, Louisiana. It runs 2.34 miles (3.77 km) in a north–south direction from LA 44 to U.S. Highway 61 (US 61) in Garyville. The route connects the community of Garyville with US 61 between New Orleans and Baton Rouge and provides a truck route for the nearby industrial plants along the Mississippi River.