Louis Frank Drucke (December 3, 1888 – September 25, 1955) was a professional baseball pitcher. He played all or part of four seasons in Major League Baseball with the New York Giants from 1909 to 1912. As a pitcher, he won 18 while losing 15 games, with a 2.90 earned run average. As a batter, he hit .178 with one home run. Drucke was the first major leaguer who attended and played at Texas Christian University (TCU).