The Little Llangothlin Nature Reserve is a protected wetland nature reserve that is located on the Northern Tablelands in the New England region of New South Wales, in eastern Australia. The 257-hectare (640-acre) reserve is situated approximately 10 kilometres (6.2 mi) north-east of the rural locality of Llangothlin, and some 20 kilometres (12 mi) north-east of Guyra.