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About: Leukoencephalopathy with neuroaxonal spheroids     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:State100024720, within Data Space : dbpedia.org associated with source document(s)

Type: ThingFuchs' dystrophyyago:WikicatBrainDisordersyago:Abstraction100002137yago:Attribute100024264yago:BrainDisorder114085708yago:Condition113920835yago:Disorder114052403yago:NervousDisorder114084880yago:PhysicalCondition114034177diseaseyago:State100024720 New Facet based on Instances of this Class

Leukoencephalopathy with neuroaxonal spheroids (LENAS) is an extremely rare kind of leukoencephalopathy and is classified as a neurodegenerative disease. LENAS is a cause of severe and subacute dementia that results from damage to certain areas of the brain. This damage is to a type of brain tissue called white matter and axon damage due to swellings which are termed spheroids. The genetic etiology of LENAS is known to follow an autosomal dominant pattern through a mutation in the CSF1R gene.