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About: Interstitial cell of Cajal     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:Brain, within Data Space : dbpedia.org associated with source document(s)

Type: Thingwikidata:Q4936952anatomical structureyago:Abstraction100002137yago:Anatomy106057539yago:Biology106037666yago:Cognition100023271yago:Content105809192yago:Discipline105996646yago:KnowledgeDomain105999266yago:LifeScience106037298yago:Morphology106078327yago:NaturalScience106000400yago:PsychologicalFeature100023100yago:Science105999797umbel-rc:AnimalBodyPartumbel-rc:Brain New Facet based on Instances of this Class

Interstitial cells of Cajal (ICC) are interstitial cells found in the gastrointestinal tract. There are different types of ICC with different functions. ICC and another type of interstitial cell, known as platelet-derived growth factor receptor alpha (PDGFRα) cells, are electrically coupled to smooth muscle cells via gap junctions, that work together as an SIP functional syncytium. Myenteric interstitial cells of Cajal (ICC-MY) serve as pacemaker cells that generate the bioelectrical events known as slow waves. Slow waves conduct to smooth muscle cells and cause phasic contractions.