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Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography. It has a peak spectral absorption at about 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. ICG binds tightly to plasma proteins and becomes confined to the vascular system. ICG has a half-life of 150 to 180 seconds and is removed from circulation exclusively by the liver to bile juice.

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  • Indocyaningrün (de)
  • Indocyanine green (en)
  • Verde indocianina (it)
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  • Indocyaningrün (ICG von englisch indocyanine green) ist ein fluoreszierender Farbstoff, der in der Medizin als Indikatorsubstanz (z. B. für die photometrische Leberfunktionsdiagnostik und Fluoreszenzangiographie) bei Herz-, Kreislauf-, Leber- und Augenerkrankungen eingesetzt wird. Dabei wird es intravenös verabreicht und in Abhängigkeit von der Leberleistung mit einer Halbwertszeit von ca. 3–4 Minuten aus dem Körper eliminiert. ICG-Natriumsalz liegt normalerweise in Pulverform vor und kann in unterschiedlichen Lösungsmitteln gelöst werden; meist wird zur besseren Löslichkeit 5 % (< 5 % je nach Charge) Natriumiodid beigegeben. Das sterile Lyophilisat einer Wasser-ICG-Lösung ist in Deutschland und den Niederlanden unter dem Namen Verdye (Hersteller: ) als Diagnostikum für die intravenöse Anw (de)
  • Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography. It has a peak spectral absorption at about 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. ICG binds tightly to plasma proteins and becomes confined to the vascular system. ICG has a half-life of 150 to 180 seconds and is removed from circulation exclusively by the liver to bile juice. (en)
  • Il verde indocianina è una tricarbocianina impiegata nelle indagini diagnostiche della gittata cardiaca, della funzionalità epatica e dell'irrorazione sanguigna epatica. Viene inoltre impiegata nella determinazione del volume plasmatico e dei parametri emodinamici di vari organi tra cui il rene, gli occhi e i polmoni. Identificazione in laboratorio: Saggi di purezza in laboratorio: 1. * Perdita all'essiccamento: 6%. 2. * Arsenico: 8 ppm. 3. * Piombo: 0,001%. 4. * Sodio ioduro: 5%. (it)
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