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In membrane biology, the Hodgkin cycle is a key component of membrane physiology that describes bioelectrical impulses, especially prevalent in neural and muscle tissues. It was identified by British physiologist and biophysicist Sir Alan Lloyd Hodgkin.

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  • Ciclo de Hodgkin (es)
  • Hodgkin cycle (en)
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  • In membrane biology, the Hodgkin cycle is a key component of membrane physiology that describes bioelectrical impulses, especially prevalent in neural and muscle tissues. It was identified by British physiologist and biophysicist Sir Alan Lloyd Hodgkin. (en)
  • En biología de membranas, el ciclo de Hodgkin es un componente clave de la fisiología de membranas que describe los impulsos bioeléctricos, especialmente prevalentes en los tejidos neurales y musculares . Fue identificado por el fisiólogo y biofísico británico Sir Alan Lloyd Hodgkin.​ (es)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Hodgkin-Cycle.jpg
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  • En biología de membranas, el ciclo de Hodgkin es un componente clave de la fisiología de membranas que describe los impulsos bioeléctricos, especialmente prevalentes en los tejidos neurales y musculares . Fue identificado por el fisiólogo y biofísico británico Sir Alan Lloyd Hodgkin.​ El ciclo de Hodgkin representa un ciclo de retroalimentación positiva en el que una despolarización inicial de la membrana conduce a una desviación incontrolada del potencial de membrana hasta cerca del VNa. La despolarización inicial debe alcanzar o superar un cierto para activar los de Na+ activados por voltaje. La apertura de los canales de Na+ permite la entrada de Na+, que, a su vez, despolariza aún más la membrana. La despolarización adicional activa canales de Na+ adicionales. Este ciclo conduce a un aumento muy rápido de la conductancia de Na+ (gNa), que mueve el potencial de membrana cerca del VNa. El ciclo se rompe cuando el potencial de membrana alcanza el potencial de equilibrio de sodio y los canales de potasio se abren para repolarizar el potencial de membrana. Este circuito de retroalimentación positiva significa que cuanto más cerca estén estos canales de Na+ activados por voltaje, menor será el umbral de .​ (es)
  • In membrane biology, the Hodgkin cycle is a key component of membrane physiology that describes bioelectrical impulses, especially prevalent in neural and muscle tissues. It was identified by British physiologist and biophysicist Sir Alan Lloyd Hodgkin. The Hodgkin cycle represents a positive feedback loop in which an initial membrane depolarization leads to uncontrolled deflection of the membrane potential to near VNa. The initial depolarization must reach or surpass a certain threshold in order to activate voltage-gated Na+ channels. The opening of Na+ channels allows Na+ inflow, which, in turn, further depolarizes the membrane. Additional depolarization activates additional Na+ channels. This cycle leads to a very rapid rise in Na+ conductance (gNa), which moves the membrane potential close to VNa. The cycle is broken when the membrane potential reaches to the sodium equilibrium potential and potassium channels open to re-polarize the membrane potential. This positive feedback loop means that the closer these voltage-gated Na+ channels are to each other, the lower the threshold of activation. (en)
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