Henry Middlebrook Crane (June 16, 1874 – January 21, 1956) was an American engineer and pioneer in the automobile industry. He was president of , vice-president and engineer of Simplex Automobile Company, and designed the Pontiac Six motor for General Motors. In its 1924 silver anniversary Issue, Automobile Trade Journal selected Crane as one of the "Creative Workers" who played a significant role in the development and advancement of the automobile.